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Surgical decompression for space-occupying cerebral infarction: Hamlet Trial

Surgical decompression for space-occupying cerebral infarction: Hamlet Trial

The prognosis for the patients with space-occupying hemispheric infarctions is poor with case fatality rates of up to 80%. In a pooled analysis of randomised trials, surgical decompression within 48 h of stroke onset reduced case fatality and improved functional outcome; however, the effect of surgery after longer intervals is unknown. The aim of HAMLET […]